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PROPRIETARY NAME & SIZES

F10SC VETERINARY DISINFECTANT
(liquid, dilute as directed, in 25L, 5L, 1L, 200ml)
(Reg No G 3070, Act 36/1947)
Australia – APVMA Approval Number: 54149
USA – EPA Registration Number: 79755-6
South Africa – DAFF Registration Number: G3070

F10SCXD VETERINARY DISINFECTANT/CLEANSER
(liquid, dilute as directed, in 25L, 5L, 1L, 200ml)
(Reg No G 3073, Act 36/1947) 
Australia – APVMA Approval Number: 59720
USA – EPA Registration Number: 79755-8
South Africa – DAFF Registration Number: G3073

F10 SKIN PREP SOLUTION
(liquid, use as is, in 5L)
(Reg No G 3105, Act 36/1947)

F10 ODOUR ELIMINATOR
(liquid, use as is in 250ml and 500ml , dilute as directed in the 5 L)
(Reg No NRCS/8054/276279/314)

F10 DISINFECTANT AEROSOL & AEROSOL FOGGER
(500ml aerosol pressurised dispensing canister, use as is)
(Reg No NRCS/8054/276279/315)

F10 DISINFECTANT SURFACE SPRAY WITH INSECTICIDE
(liquid, use as is, in 25L, 5L and 1L)
(Reg No NRCS/8054/276279/311)
UK – HSE Approval Number: 9362

F10 WIPES
(100 impregnated cellulose tissues)
(Reg No NRCS/8054/276279/316)

COMPOSITION
The core actives of all the disinfectant products are quaternary ammonium compound, with non toxic ampholytic surfactants and sequestrants.

LEVEL OF ACTIVES OTHER pH*
F10SC VETERINARY DISINFECTANT​  
QAC 54,0g/L Ampholytic surfactants and sequestrants
Water to balance		 7.5
F10SCXD VETERINARY DISINFECTANT/CLEANSER  
QAC 54,0g/L Ampholytic surfactants, sequestrants/detergents Fragrance
Water to balance		 7.5
F10 SKIN PREP SOLUTION  
QAC 0,44g/L Ampholytic surfactants and sequestrants
Alcohol 20%
Water to balance		 6.5
F10 ODOUR ELIMINATOR  
QAC 0,21g/L Ampholytic surfactants and sequestrants
Fragrance
Water to balance		 6.6
F10 DISINFECTANT AEROSOL & AEROSOL FOGGER  
QAC 0,72g/L Ampholytic surfactants and sequestrants
propellant		 6.5
F10 DISINFECTANT SURFACE SPRAY WITH INSECTICIDE  
QAC 1,07g/L
Cypermethrin 2,5g/L		 Ampholytic surfactants and sequestrants 7.5
F10 WIPES  
QAC 0,43g/L Ampholytic surfactants and sequestrants 7.5

* The pH value refers to the packed concentration

INDICATIONS
A broad spectrum biocide effective against bacteria, fungi, viruses and bacterial and fungal spores.

BACTERIA
(gram positive and
gram negative (spp)		 FUNGI,
YEASTS and
MOULDS (spp) 		VIRUSES
(enveloped and
non-enveloped)		 SPORES
(bacterial and
fungal) spp
Acinetobacter Listeria Aspergillus Adenovirus Aspergillus
Campylobacter MRSA Candida Avian Influenza
H5N2 HPA1		 Bacillus
Chlamydophila Mycobacterium Microsporum Canineparvovirus Microsporum
Clostridium Mycoplasma Penicillium Circovirus Penicillium
Cholera Micrococcus Trichophyton Enterovirus Trichophyton
Corynebacterium Ornitobacteriun
Rhinotracheale		   Foot and Mouth Disease  
Citrobacter Pasteurella   Feline Herpesvirus  
Entercoccus Proteus vulgaris   Hepatitis B  
Enterobacter Pseudomonas   HIV  
Escherichia coli Salmonella   IBD  
Klebsiella Staphylococcus   Newcastle Disease  
Leptospira Streptococcus   Rabies  

*FMDV is effectively eliminated with the pH buffered product F10CL General Farm Disinfectant

APPLICATIONS
The core product F10SC VETERINARY DISINFECTANT is a high performance surface acting biocidal compound and due to its inherently low toxicity and low irritation characteristics is widely used within the veterinary profession in companion and large animal practices, referral hospitals, zoo’s, laboratories, and various other institutions. It is used in numerous applications, i.e. cold sterilisation of instruments and equipment including endoscopes, intravenous catheters, and endotracheal tubes; high level disinfection of hard surfaces and air spaces, water treatment, and as a sanitising rinse for solid food and fruit. Fogging with F10SC VETERINARY DISINFECTANT, (a spray of fine mist-like droplets) has been shown to be 100% effective in eliminating airborne micro-organisms.
 
F10SCXD VETERINARY DISINFECTANT/CLEANSER is used for hard surface disinfection and cleaning of lightly soiled areas such as kennels and cages.
 
F10SC VETERINARY DISINFECTANT has been successfully used in aerosol fogging applications in the presence of animals as well as a number of clinical
applications including nebulising in respiratory tract Aspergillosis infections, wound irrigation, and nasal flushing.
 
F10 SKIN PREP SOLUTION is a pre-op skin decontaminant.
 
F10 ODOUR ELIMINATOR is a hard surface and aerosol high level disinfectant with a masking pine fragrance.
 
F10 DISINFECTANT AEROSOL & AEROSOL FOGGER is available with on/off and total evacuation actuators for use as a hard surface and air space disinfectant.
Tests have shown that aerosol disinfection is an effective method of carrying out high level disinfection of air spaces.
 
F10 DISINFECTANT SURFACE SPRAY WITH INSECTICIDE is a hard surface disinfectant for animal housing, effective against flying and crawling insects such as blow flies, biting flies, fleas, midges, mites, mosquitoes and ticks.
 
F10 WIPES are disinfectant impregnated surface wipes for use on equipment such as thermometers, and for hand decontamination when washing facilities are
unavailable.
 
ANTIMICROBIAL ACTION
The antimicrobial action mechanism of the F10 branded disinfectants is taken from each component separately but in addition is due to the additive synergistic action of all components combined.
 
Bactericidal tests have been carried out in accordance with SANS 636-2001 – Standard (South African) having a performance pass criteria of >log3 reduction in microbial counts, the AFNOR Standard (French)which is a>log4 reduction in microbial counts, the European Union EN Standard which is a >log5 reduction in microbial counts, and the AOAC Standard (USA) which is a >log6 (1,000,000 times) reduction in microbial counts. MIC in-vitro tests have shown significant depth of performance as indicated. Generally testing was carried out at ambient temperatures with the exception of EN Standard tests where some were carried out at low temperatures 10o C and some DEFRA tests at 4o C. The EN Standard for low temperatures is 10o C and at this temperatures bactericidal performance was equal to that at ambient temperatures , however there was a significant fall off in performance at 4o C. Other tests carried out at elevated temperatures of 45o C showed a significant increase in performance.

FIGURE A: THE F10SC MIC VALUES

Test organism Concentration of F10SC (dilution) that
visual inhibition of the Test organism = MIC value
resulted incomplete
Pseudomonas aeruginosa – ATCC 27853 A dilution of 1/1000 or 0,1 % F10SC
Escherichia coli – ATCC 25922 A dilution of 1/4000 or 0,025 % F10SC
Staphylococcus aureus – ATCC 25923 A dilution of 1/16000 or 0,00625 % F10SC
Klebsiella pneumoniae – ATCC 10031 A dilution of 1/4000 or 0,025 % F10SC
Staphylococcus aureus -MRSA Local isolate A dilution of 1/16000 or 0,00625 % F10SC
Pasteurella multocida – Local isolate A dilution of 1/16000 or 0,00625 % F10SC
Enterococcus faecalis – ATCC 29212 A dilution of 1/16000 or 0,00625 % F10SC

Fungicidal tests have been carried out in accordance with SANS 636-2001,AFNOR and EN Standards which require a log3 and log4 reduction in microbial counts respectively.

Virucidal tests have been carried out in accordance with various internationally accepted protocols by the UP Faculty of Veterinary Science’s Department of Poultry Diseases, the Department of Veterinary Tropical Diseases and the ARC – Onderstepoort Veterinary Institute. The FMDV test was carried in accordance with the DEFRA (UK) Standard (F10CL General Farm Disinfectant only). Test requirements called for log4 and log 5 reduction in microbial counts.

Sporicidal tests have been carried out in accordance with EN 13704-2002, 13697- 2001 and 1650-1997 Standards which required a log5 reduction in microbial counts.

CONCENTRATIONS AND CONTACT TIMES
Concentrations and contact times are indicated on each product label. It should be noted that additional tests were carried out to determine various speed of kill rates to meet varying application demands.

Bactericidal test standard contact times are generally 5 minutes. However it was found that a log3 reduction in gram positive bacteria was   achieved in 30 seconds and similarly 60 seconds for gram negative bacteria all at a concentration of 1:500 of the F10SC Veterinary Disinfectant. In the AOAC test a log6 reduction was achieved
in both gram positive and gram negative bacteria in a 10 minutes contact time.

DOSAGE AND DIRECTIONS FOR USE
For F10SC VETERINARY DISINFECTANTS clear away debris and rinse surfaces, then apply as below :

–  Environmental general disinfection dilute 1:500 (2 ml / l water)
– High level disinfection (including fungal spores) dilute 1:250 (4 ml / l water)
– Resistant viruses and bacterial spores dilute 1:100 (10 ml / l water)
– Sterilisation of instruments/equipment dilute 1:100 (10 ml / l water)

Additional information is available in application user guidelines. For other products refer to each specific product label.

TOXICOLOGY
Studies were carried out by a GLP laboratory in accordance with OECD and EPA guidelines.

 
Toxicity Packed Concentrate Use Dilutions (1:100 and higher)
Acute Oral Toxicity: (Rat) Toxicity >2000mg per kg No toxicity (>200 000mg per kg)
Acute Dermal Toxicity: (Rat) Toxicity >5000mg per kg No toxicity (>500 000mg per kg)
Acute Eye Irritation Causes serious eye damage None
Acute Dermal Irritation None None
Acute Inhalation Toxicity None None
Skin Sensitization Not a skin sensitizer Not a skin sensitizer
Carcinogenicity,
mutagenicity
and toxicity for reproduction		 Based on data for the raw materials, no carcinogenic, mutagenic
or toxicity for reproduction is predicted.
Acute inhalation toxicity 
After taking account of the relative volatility, acute oral toxicity, dosage form and direction for use the inhalation toxicity of F10 disinfectant products will not be greater than the values shown for acute oral toxicity.
Residual toxicity 
Five-week supervised trial using day-old broiler chicks restricted to 1:1000 and 1:250 solutions of F10SC in drinking water showed no F10 residual build-up in muscle meat, liver or kidneys.
 
CORROSION 
The F10 Veterinary Disinfectants are non-corrosive at the recommended dilutions(complies with SABS test 1615 on polished aluminium strip after 30 days).
 
FREE RINSING 
All F10SC Veterinary Disinfectants are free rinsing at recommended dilutions(complies with SABS test 1593 6.11).
 
WATER INSOLUBLE MATTER CONTENT
The water insoluble matter content of F10SC Veterinary Disinfectants and F10 Skin Prep Solution is 0,3g/litre (complies with SABS 1593 6.12).
 
BIODEGRADABLE 
The F10SC Veterinary Disinfectants when used at recommended dilutions have a zero rating in terms of EU standards.
 
PRECAUTIONS 
Ingestion: Do not induce vomiting, give milk or water to drink. Eye contact: Rinse eyes with water, seek medical advice if necessary. In spraying and aerosol/fogging applications it is advisable to wear a disposable mask over mouth, nose and eye
protection.
 
WARNINGS
Do not mix with soap or other chemicals. Avoid contact with eyes. Keep out of reach of children, uninformed persons and pets. F10 Aerosol Disinfectant is a highly flammable aerosol. Avoid contact with felines when using F10 Disinfectant Surface Spray with Insecticide.
 
PRESENTATION
HDPE bottles of varying sizes except for the F10 Aerosols which are in pressurized metal canisters and the F10 Wipes which are packed into a sealed plastic bag.
 
STORAGE INSTRUCTION
Store below 30oC in dry conditions, out of direct sunlight.
 
REGISTRATION HOLDER
Health and Hygiene (Pty) Ltd. PO Box 906, Florida Hills, 1716, South Africa
 
MANUFACTURED BY
Health and Hygiene (Pty) Ltd in accordance with GMP (Good Manufacturing Practice) license reference M-7586 issued by APVMA and SABS 636 Permit 6656/9863.
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